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Single-Nucleotide Polymorphisms in Exonic and Promoter Regions of Transcription Factors of Second Heart Field Associated with Sporadic Congenital Cardiac Anomalies.
Wang E, Fan X, Nie Y, Zheng Z, Hu S. Wang E, et al. Balkan J Med Genet. 2022 Jun 5;24(2):39-47. doi: 10.2478/bjmg-2021-0028. eCollection 2021 Nov. Balkan J Med Genet. 2022. PMID: 36249516 Free PMC article.
The minor alleles of GATA5: rs41305803 G>A and MEF2C: rs304154 A>G increased the risk of tetralogy of Fallot (TOF). The minor alleles of TBX20: rs336284 A>G and SMYD1: rs88387557 T>G only increased the risk of a single ventricle (SV). Luciferase assays revealed …
The minor alleles of GATA5: rs41305803 G>A and MEF2C: rs304154 A>G increased the risk of tetralogy of Fallot (TOF). The minor alleles …
DNA methylation profiles at precancerous stages associated with recurrence of lung adenocarcinoma.
Sato T, Arai E, Kohno T, Tsuta K, Watanabe S, Soejima K, Betsuyaku T, Kanai Y. Sato T, et al. PLoS One. 2013;8(3):e59444. doi: 10.1371/journal.pone.0059444. Epub 2013 Mar 27. PLoS One. 2013. PMID: 23544068 Free PMC article.
The aim of this study was to clarify the significance of DNA methylation alterations at precancerous stages of lung adenocarcinoma. Using single-CpG resolution Infinium array, genome-wide DNA methylation analysis was performed in 36 samples of normal lung tissue obt …
The aim of this study was to clarify the significance of DNA methylation alterations at precancerous stages of lung adenocarcinoma. U …
Reversal of Right Ventricular Hypertrophy and Dysfunction by Prostacyclin in a Rat Model of Severe Pulmonary Arterial Hypertension.
Vanderpool RR, Gorelova A, Ma Y, Alhamaydeh M, Baust J, Shiva S, Tofovic SP, Hu J, Nouraie SM, Gladwin MT, Sharifi-Sanjani M, Al Ghouleh I. Vanderpool RR, et al. Int J Mol Sci. 2022 May 12;23(10):5426. doi: 10.3390/ijms23105426. Int J Mol Sci. 2022. PMID: 35628236 Free PMC article.
However, custom RNA array analysis revealed amelioration of SuCH-associated increases in newly identified TBX20 as well as the fibrotic markers collagen1alpha1 and collagen 3alpha1 upon treprostinil treatment. ...
However, custom RNA array analysis revealed amelioration of SuCH-associated increases in newly identified TBX20 as well as the fibrot …